Impact on Sexual Function of Holmium Laser Enucleation Versus Transurethral Resection of the Prostate: Results of a Prospective, 2-Center, Randomized Trial
Briganti A, Naspro R, Gallina A, Salonia A, Vavassori I, Hurle R, Scattoni E, Rigatti P, Montorsi F. J Urol 2005;174:1913-1916; J Urol. 2006; 175:1817-1821.
KEY WORDS: penis, impotence, lasers, prostate, prostatic hyperplasia
TURP has been considered the reference standard for BPH for the last 30 years.1 Currently HoLEP seems to be an attractive alternative to standard TURP. To the knowledge of the authors, sexual function in men who undergo TURP or HoLEP has never been assessed in prospective, randomized fashion using validated instruments. Thus, Briganti and coll compared the impact of the 2 procedures on a total of 120 patients with a mean age SD of 65.2 ± 7.1 years who had benign prostatic hyperplasia at the 12 and 24-month follow-up visits.
- A total of 32 patients (53.3%) in group 1 and 31 (51.6%) in group 2 reported various degrees of erectile dysfunction before surgery according to the IIEF-EF score, with significant differences between preoperative and postoperative orgasmic domain scores in each group. The prevalence of subjectively reported postoperative retrograde ejaculation was significantly higher than at baseline assessment in the 2 groups with no differences between the 2 surgical procedures.
- TURP and HoLEP significantly lowered the IIEF orgasmic function domain with no differences between techniques. This was caused by retrograde ejaculation.
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