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Prevalence of Peyronie’s Disease Among Patients With Erectile Dysfunction

El-Sakka AL; Eur Urol. 2006; 49:564–569.

KEY WORDS: Erectile dysfunction, Risk factors, Peyronie’s disease

Although many theories have been proposed to explain the cause of Peyronie's Disease (PD), the true pathogenesis of the disease remains obscure. As a result, the etiology and pathogenesis of erectile dysfunction (ED) in patients with PD remains also unsettled. Furthermore, the association between the two conditions is in the focus of interest for many researchers. To assess the prevalence of PD among patients with erectile dysfunction, the authors enrolled and interviewed a total of 1,440 male patients with ED.

• Mean ages  SD were 54.1 ± 6.9 (range 42–71) and 52.5 ± 11.9 (range 20–84) years for patients with and without PD respectively. Of the patients, 11.8% had mild, 38.3% had moderate and 49.9% had severe ED. 7.9% of the patients had PD. Significant associations between PD and both the longer duration and the increased severity of ED were detected. There were also significant associations between PD and the following socio-demographic risk factors of ED: age, obesity, smoking, duration and number of cigarettes smoked per day. Concomitant diseases and medical comorbidities such as diabetes, dyslipidemia, psychological disorders and the presence of at least one risk factor were significantly associated with PD in patients with ED.
• Peyronie’s disease was not rare among the study population. There were significant associations between ED risk factors and PD. Further studies are needed to investigate how much ED and PD influence each other.

See the abstract

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16386353&query_hl=5&itool=pubmed_docsum